Answer BOF 33

 

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BOF: 33

A 69-year-old male who is known to have ulcerative colitis has been found to be mildly anaemic and has a high ESR.

His colitis is quiescent with a normal bowel habit and his last surveillance colonoscopy was normal. He is not jaundiced nor does he have fever.

There are no abnormalities found on clinical examination.

Investigations reveal:

Hb 11.5 g/L

WCC 4.7

PLT 168

Corrected Calcium 2.60

IgG 26 (6-13)

IgA 1.6(0.9-3)

IgM 1.5 (0.4-2.2)

Which of the following investigation would you arrange next?

a)      Colonoscopy

b)      Magnetic Resonance Cholangio Pancreatography

c)      Isotope bone scan

d)      Plasma protein electrophoresis

e)      Chest x-ray

Answer:

d)

The patient has quiescent ulcerative colitis and does not appear to have any complication in relation to this. In an elderly patient with an elevated ESR, elevated calcium, immunoglobulins and mild anaemia one would consider a diagnosis of multiple myeloma and hence plasma protein electrophoresis would be the investigation of choice.

Last Updated: 16/04/06

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